Associate Scientist II, Analytical Development

Company: Vaxcyte
Location: San Carlos
Posted on: November 8, 2024

Job Description:

Join our Mission to Protect Humankind!Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, periodontitis, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

• AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
• LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
• RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
• MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality, and clarity across communications and decision making.Summary: Looking for an energetic and talented individual to join our Analytical Development team. Primary responsibility for the incumbent will be to support the developmental activities currently ongoing in the laboratory as assigned.Essential Functions:

• Assist in the design, execution, and interpretation of experiments to analyze drug substances and intermediates including:
• HPLC/LC-MS, IC, with experience in Chemstation
• Microplate assays
• SDS-PAGE, ELISA
• SEC-MALS
• GC-MS
• Assist in analytical method development of new assays.
• Support PCV stability programs on analyzing stability samples in a timely manner.
• Knowledge of capillary electrophoresis and/or experience in use of such would be a plus.
• Keep accurate and detailed records of experiments in laboratory notebooks.
• Summarize data and communicate to the analytical team.
• Work within a team environment and provide support to further team objectives.Requirements:
  • B.S. in Chemistry, Analytical Chemistry preferred, Organic/Biochemistry considered with 2-6 years of relevant experience, or MS with 1-4 years of experience.
  • The ideal candidate will have a background in analytical chemistry principles and hands-on experience with modern analytical instrumentation commonly used in the analysis and characterization of drug candidates. Candidates with other scientific disciplines may be considered based on relevant experience.
  • Experience in chemical/biological/immunological assays such as HPLC/UV and other spectrometric methodology, ELISA, Western blots, CE-SDS, and SDS-PAGE.
  • Experience in conjugate and carbohydrate analysis desired, for example in HPAEC-PAD, colorimetric methods, HPLC, SEC, and LC-MS.
  • Understanding of basic principles of analytical method development/validation/qualification concepts.
  • Attention to detail and excellent skills in record keeping/documentation. Critical thinking and ability to analyze data.
  • Strong interpersonal skills; ability to communicate effectively both verbally and in written formats.
  • Ability to work under supervision in a fast-paced, cross-functional environment and collaborate effectively with other team members. Eagerness and ability to learn and understand new concepts with ease.Reports to: Senior Scientist, Analytical DevelopmentLocation: San Carlos, CACompensation:The compensation package will be competitive and includes comprehensive benefits and an equity component.Salary Range: $105,000 - $114,000Send resumes to: Vaxcyte, Inc.825 Industrial Road, Suite 300San Carlos, CA 94070We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.
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Keywords: Vaxcyte, Mountain View , Associate Scientist II, Analytical Development, Other , San Carlos, California